Dekut conducts R&D in life sciences in cooperation with Hungarian
and international partners. Most of our researchers work for Dekut NPO as a
volunteer.
Our research team performs
basic and applied research as well, however, we don’t wish to participate in
projects of which the aim or the usefulness of the results is undefined, and
whose justification is not sufficiently substantiated by clinical,
epidemiological or economic arguments.
1.)
Research on genomics
The principle of genomics is to examine the genome
and gene interactions by bioinformatics methods. One form of bioinformatics
databases are the biobanks which contain in addition to the clinical data of a
certain group of patients their tissue samples as well. On these tissue samples
different molecular biological tests may be made later. The analysis of the
emergent databases and the biological interpretation of data are great
challenges for researchers. Dekut contributes
actively to create biobanks, to generate biochemical databases, and to analyse
their data. During the data processing we apply state-of-the-art
statistical and data mining methods.
Our researches’ aims on
genomics are to create searchable sequence databases and search engines to answer
well defined biological questions (for example to search miRNA targets), so as
to allow the identification of new therapeutic targets, nucleic acid-based
diagnostic tools and medical products.
The main line of basic
research project includes disease-specific subprojects, such as our encourage
projects on examining regulatory disorders of miRNAs in colon cancer and
thrombophiliae.
2.) Health economics
Decision
makers in healthcare often face the following problem: there are existing and
adequate models in health economics that would enable them to answer specific
questions but the relevant data is either missing or unreliable.
Dekut
supports the development of innovative and new examination methods as well as
the related tools within health economics.
Methodology,
toolkit and examination planning for measuring quality of life.
Health
economics of patient compliance (including methodology and toolkit for drug compliance monitoring and
electronic patient compliance monitoring).
Economics
of telemedicine models (toolkit, protocols, fitting telemedicine in the
existing system of medical attendance, cost-effectiveness, confidence levels)
Evaluation
of medical technologies.
Inclusion and utilization of results in basic and industrial research
into medical practice.